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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:41.6 nTPM
HPA:41.6 nTPM
FANTOM5:7.4 Scaled Tags Per Million
Pig:25.3 nTPM
Allen mouse:6.0 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 41.6
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 37.4
1984 Male, age 76, both hemispheres 38.5
2301 Female, age 85, both hemispheres 37.2
2188 Female, age 91, both hemispheres 37.0
2090 Male, age 80, both hemispheres 36.8
Dorsal cochlear nucleus
nTPM: 38.2
2370 Male, age 61, both hemispheres 40.3
2187 Female, age 91, both hemispheres 38.9
2802 Male, age 74, right hemisphere 38.2
2378 Male, age 80, both hemispheres 37.1
2058 Male, age 76, both hemispheres 36.6
Dorsal tegmental nucleus
nTPM: 38.6
1936 Male, age 76, left hemisphere 39.2
2358 Male, age 61, both hemispheres 39.1
2083 Male, age 80, both hemispheres 38.4
2326 Male, age 74, both hemispheres 37.6
Dorsolateral tegmental area
nTPM: 40.0
2751 Female, age 85, both hemispheres 44.4
2141 Male, age 76, both hemispheres 42.7
2360 Male, age 74, both hemispheres 38.3
2654 Male, age 80, both hemispheres 37.8
2337 Male, age 61, both hemispheres 36.7
Kolliker-Fuse nucleus
nTPM: 37.8
2163 Male, age 80, both hemispheres 38.6
2793 Female, age 91, left hemisphere 37.5
2315 Male, age 76, right hemisphere 37.1
Lateral lemniscal nuclei
nTPM: 36.3
2320 Female, age 91, left hemisphere 37.3
2453 Male, age 74, right hemisphere 36.5
2169 Male, age 76, both hemispheres 36.1
2036 Male, age 80, both hemispheres 35.9
2746 Female, age 85, left hemisphere 35.9
Lateral parabrachial nucleus
nTPM: 37.0
2790 Male, age 61, both hemispheres 38.7
2013 Male, age 80, both hemispheres 36.9
2139 Female, age 85, right hemisphere 36.3
2792 Male, age 76, both hemispheres 36.2
Lateral vestibular nucleus
nTPM: 39.1
2311 Male, age 80, both hemispheres 39.7
2184 Male, age 76, both hemispheres 38.5
Locus coeruleus
nTPM: 40.5
2720 Male, age 74, both hemispheres 42.7
2162 Male, age 80, both hemispheres 41.2
2123 Female, age 91, both hemispheres 40.9
2788 Male, age 74, unknown 40.9
1980 Male, age 76, both hemispheres 39.4
2014 Male, age 55, unknown 39.2
2317 Female, age 72, unknown 39.1
Medial olivary nucleus
nTPM: 36.4
2138 Female, age 91, both hemispheres 37.2
2851 Male, age 80, both hemispheres 36.4
1943 Male, age 61, both hemispheres 36.3
1962 Male, age 76, both hemispheres 35.8
Medial parabrachial nucleus
nTPM: 40.8
2463 Female, age 85, right hemisphere 46.4
2170 Female, age 91, both hemispheres 40.6
2786 Male, age 76, both hemispheres 39.7
2854 Male, age 80, both hemispheres 38.8
2156 Male, age 61, both hemispheres 38.3
Medial periolivary nuclei
nTPM: 36.1
2791 Male, age 74, right hemisphere 36.8
2458 Female, age 91, both hemispheres 36.6
2081 Male, age 80, both hemispheres 36.0
2171 Female, age 85, both hemispheres 35.6
2063 Male, age 76, both hemispheres 35.5
Motor facial nucleus
nTPM: 36.5
2126 Male, age 61, both hemispheres 37.9
2795 Female, age 91, both hemispheres 37.0
2365 Male, age 74, right hemisphere 36.4
2697 Female, age 85, both hemispheres 36.2
2327 Male, age 80, both hemispheres 35.8
2062 Male, age 76, both hemispheres 35.5
Motor trigeminal nucleus
nTPM: 38.2
2309 Male, age 76, both hemispheres 40.1
2335 Male, age 61, both hemispheres 39.9
2321 Female, age 91, both hemispheres 37.7
2560 Male, age 74, both hemispheres 37.6
2079 Male, age 80, both hemispheres 35.9
Nuclei of the trapezoid body
nTPM: 35.9
2368 Female, age 91, both hemispheres 36.6
2166 Male, age 80, both hemispheres 36.0
2159 Male, age 61, both hemispheres 35.9
1983 Male, age 76, both hemispheres 35.5
2735 Female, age 85, both hemispheres 35.5
Paramedian reticular nucleus
nTPM: 37.1
2313 Male, age 61, both hemispheres 37.6
2050 Female, age 85, both hemispheres 37.4
2057 Male, age 80, both hemispheres 36.9
2052 Male, age 76, both hemispheres 36.5
Pontine nuclei
nTPM: 36.0
2319 Female, age 91, both hemispheres 37.1
2454 Male, age 74, left hemisphere 36.4
2115 Male, age 80, left hemisphere 36.0
2727 Male, age 61, right hemisphere 35.9
2787 Female, age 85, both hemispheres 35.8
1863 Male, age 55, unknown 35.7
1968 Male, age 76, left hemisphere 35.6
2109 Female, age 72, unknown 35.6
Pontine raphe nucleus
nTPM: 40.6
2853 Male, age 76, midline 43.4
2122 Female, age 85, midline 37.8
Posteroventral cochlear nucleus
nTPM: 38.0
2752 Female, age 85, both hemispheres 39.9
2371 Male, age 61, both hemispheres 39.2
2070 Male, age 76, both hemispheres 37.3
2135 Female, age 91, both hemispheres 36.9
2341 Male, age 80, both hemispheres 36.4
Principal sensory trigeminal nucleus
nTPM: 36.6
2324 Male, age 76, both hemispheres 37.7
2367 Female, age 91, left hemisphere 36.5
2158 Male, age 61, both hemispheres 36.3
2008 Male, age 80, left hemisphere 35.8
Reticular pontine nucleus, caudal
nTPM: 36.9
2559 Male, age 74, both hemispheres 39.0
2457 Female, age 91, both hemispheres 37.0
2332 Male, age 80, right hemisphere 36.2
2092 Male, age 76, both hemispheres 35.6
Reticular pontine nucleus, oral
nTPM: 40.1
2167 Male, age 76, both hemispheres 46.6
1939 Male, age 80, both hemispheres 43.9
2012 Female, age 85, both hemispheres 38.0
2366 Female, age 91, both hemispheres 36.9
2361 Male, age 74, both hemispheres 35.3
Reticulotegmental nucleus
nTPM: 38.4
2322 Female, age 91, both hemispheres 39.3
2325 Male, age 76, both hemispheres 39.2
2452 Male, age 74, both hemispheres 37.6
2333 Male, age 80, both hemispheres 37.5
Spinal trigeminal nucleus, oral
nTPM: 41.6
1978 Male, age 76, both hemispheres 47.7
2737 Female, age 85, both hemispheres 40.2
2164 Male, age 80, both hemispheres 37.1
Subcoeruleus area
nTPM: 39.6
2369 Female, age 85, left hemisphere 42.8
2323 Female, age 91, left hemisphere 41.5
2451 Male, age 74, both hemispheres 39.6
1958 Male, age 80, both hemispheres 37.7
2089 Male, age 76, left hemisphere 36.5
Superior olive
nTPM: 36.3
2561 Female, age 91, both hemispheres 37.3
2364 Male, age 74, right hemisphere 36.6
1875 Female, age 85, both hemispheres 36.1
2329 Male, age 80, right hemisphere 35.9
2020 Male, age 76, both hemispheres 35.8
Superior vestibular nucleus
nTPM: 38.1
2383 Male, age 74, both hemispheres 38.3
2015 Male, age 80, both hemispheres 38.1
2061 Male, age 76, both hemispheres 37.8
Ventral periolivary nuclei
nTPM: 36.0
2794 Female, age 91, left hemisphere 37.1
2023 Male, age 76, both hemispheres 35.7
2165 Male, age 80, both hemispheres 35.7
2130 Female, age 85, both hemispheres 35.6
Ventrolateral tegmental area, A5 NE cell group
nTPM: 36.9
2359 Male, age 61, both hemispheres 39.2
2840 Female, age 85, both hemispheres 37.0
2456 Female, age 91, both hemispheres 36.8
2449 Male, age 74, both hemispheres 36.7
2161 Male, age 80, both hemispheres 36.1
1959 Male, age 76, both hemispheres 35.6

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 7.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 5.5
FF:10165-103B3 76 years, female 7.9
FF:10182-103D2 60 years, female 3.1
Pons
Scaled Tags Per Million: 7.4
FF:10033-101E6 18-54 years, mixed 7.4

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 25.3
Pig sample Sample description nTPM
Pons
nTPM: 25.3
Samples: 4

Max nTPM: 47.6
Min nTPM: 14.9
Sample A Female 47.6
Sample B Female 14.9
Sample C Male 15.1
Sample D Male 23.5

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.0
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 6.0
72129291 Antisense, RP_051017_03_F07, Mouse strain C57BL/6J (56 days, male) 6.2
75750508 Antisense, RP_060518_04_H10, Mouse strain C57BL/6J (56 days, male) 5.8

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.