ADORA3

GENE INFORMATION

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Gene name

ADORA3 (HGNC Symbol)

Synonyms

AD026

Description

adenosine A3 receptor (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

112025970 - 112106584

Ensembl

ENSG00000121933 (version 73.37)

Entrez gene

140

UniProt

P33765 (UniProt - Evidence at transcript level), Q6P2N6 (UniProt - Evidence at transcript level)

neXtProt

NX_P33765, NX_Q6P2N6

Antibodypedia

ADORA3 antibodies
 

PROTEIN VIEW

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ADORA3-001
 
ADORA3-002
 
ADORA3-003
 
ADORA3-006
 
ADORA3-007
 
ADORA3-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADORA3-001 ENSP00000358731
ENST00000369717
Q6P2N6
Show all »
Show » Show » 266 30.3 No 2
ADORA3-002 ENSP00000406102
ENST00000442484
115 12.7 No 0
ADORA3-003 ENSP00000415646
ENST00000414219
Show » 207 23.4 No 1
ADORA3-006 ENSP00000398770
ENST00000443498
Q5QNY8
Show all »
Show » 172 19.6 No 1
ADORA3-007 ENSP00000358730
ENST00000369716
P33765
Show all »
Show » Show » 347 39 No 5
ADORA3-010 ENSP00000241356
ENST00000241356
P33765
Show all »
Show » Show » 318 36.2 No 7