MRPS2

GENE INFORMATION

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Gene name

MRPS2 (HGNC Symbol)

Synonyms

CGI-91

Description

mitochondrial ribosomal protein S2 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

Chromosome

9 (Chromosome progress)

Cytoband

q34.3

Chromosome location (bp)

138391830 - 138396519

Ensembl

ENSG00000122140 (version 73.37)

Entrez gene

51116

UniProt

Q9Y399 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y399

Antibodypedia

MRPS2 antibodies
 

PROTEIN VIEW

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MRPS2-001
 
MRPS2-007
 
MRPS2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS2-001 ENSP00000360850
ENST00000371785
Q9Y399
Show all »
Show » Show » 296 33.2 No 0
MRPS2-007 ENSP00000400082
ENST00000453385
Q5T8A0
Show all »
Show » 270 30.5 No 0
MRPS2-201 ENSP00000241600
ENST00000241600
Q9Y399
Show all »
Show » Show » 296 33.2 No 0