PLG

GENE INFORMATION

? »

Gene name

PLG

Synonyms

Description

plasminogen (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]

Chromosome

6 (Chromosome progress)

Cytoband

q26

Chromosome location (bp)

161123270 - 161174338

Ensembl

ENSG00000122194 (version 73.37)

Entrez gene

5340

UniProt

P00747 (UniProt - Evidence at protein level)

neXtProt

NX_P00747

Antibodypedia

PLG antibodies
 

PROTEIN VIEW

? »
 
 
 
PLG-001
 
PLG-002
 
PLG-006
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLG-001 ENSP00000308938
ENST00000308192
P00747
Show all »
Show » Show » 810 90.6 Yes 0
PLG-002 ENSP00000355891
ENST00000366924
Q5TEH5
Show all »
136 15.4 Yes 0
PLG-006 ENSP00000389424
ENST00000418964
A6PVI2
Show all »
Show » 166 18.7 Yes 0