DNAI1

GENE INFORMATION

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Gene name

DNAI1 (HGNC Symbol)

Synonyms

CILD1, DIC1, PCD

Description

dynein, axonemal, intermediate chain 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Chromosome

9 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

34457412 - 34520982

Ensembl

ENSG00000122735 (version 73.37)

Entrez gene

27019

UniProt

Q9UI46 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UI46

Antibodypedia

DNAI1 antibodies
 

PROTEIN VIEW

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DNAI1-001
 
DNAI1-002
 
DNAI1-006
 
DNAI1-007
 
DNAI1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNAI1-001 ENSP00000242317
ENST00000242317
Q9UI46
Show all »
Show » 699 79.3 No 0
DNAI1-002 ENSP00000395396
ENST00000437363
Q5T8G8
Show all »
289 32.7 No 0
DNAI1-006 ENSP00000408129
ENST00000442556
Show » 142 16 No 0
DNAI1-007 ENSP00000434296
ENST00000470169
Show » 175 19.7 No 0
DNAI1-201 ENSP00000443667
ENST00000545019
B7Z7U1
Show all »
Show » 168 19.3 No 2