AKR1D1

GENE INFORMATION

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Gene name

AKR1D1 (HGNC Symbol)

Synonyms

SRD5B1

Description

aldo-keto reductase family 1, member D1 (HGNC Symbol)

Entrez gene summary

The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]

Chromosome

7 (Chromosome progress)

Cytoband

q33

Chromosome location (bp)

137687070 - 137802732

Ensembl

ENSG00000122787 (version 73.37)

Entrez gene

6718

UniProt

P51857 (UniProt - Evidence at protein level)

neXtProt

NX_P51857

Antibodypedia

AKR1D1 antibodies
 

PROTEIN VIEW

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AKR1D1-001
 
AKR1D1-002
 
AKR1D1-006
 
AKR1D1-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AKR1D1-001 ENSP00000402374
ENST00000411726
P51857
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Show » Show » 285 32.9 No 0
AKR1D1-002 ENSP00000242375
ENST00000242375
P51857
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Show » Show » 326 37.4 No 0
AKR1D1-006 ENSP00000389197
ENST00000432161
P51857
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Show » Show » 290 32.7 No 0
AKR1D1-009 ENSP00000397042
ENST00000438242
C9J3U1
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96 11 No 0