CIT

GENE INFORMATION

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Gene name

CIT (HGNC Symbol)

Synonyms

CRIK, KIAA0949, STK21

Description

citron (rho-interacting, serine/threonine kinase 21) (HGNC Symbol)

Entrez gene summary

This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Chromosome

12 (Chromosome progress)

Cytoband

q24.23

Chromosome location (bp)

120123595 - 120315095

Ensembl

ENSG00000122966 (version 73.37)

Entrez gene

11113

UniProt

O14578 (UniProt - Evidence at protein level)

neXtProt

NX_O14578

Antibodypedia

CIT antibodies
 

PROTEIN VIEW

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CIT-001
 
CIT-005
 
CIT-006
 
CIT-008
 
CIT-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CIT-001 ENSP00000261833
ENST00000261833
O14578
Show all »
Show » Show » 2027 231.4 No 0
CIT-005 ENSP00000376306
ENST00000392521
O14578
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Show » Show » 2069 236.6 No 0
CIT-006 ENSP00000376305
ENST00000392520
Show » 1640 187.3 No 0
CIT-008 ENSP00000443199
ENST00000536325
H0YGG8
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Show » 109 12.6 No 0
CIT-011 ENSP00000446105
ENST00000546026
F5H4K4
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162 18.8 No 0