ITPR2

GENERAL INFORMATION

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Gene name

ITPR2

Gene description

Inositol 1,4,5-trisphosphate receptor, type 2

Protein class

Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Normal tissues displayed weak to moderate cytoplasmic staining with additional membranous or nuclear positivity in few tissues. Renal tubules, glandular cells of breast, parathyroid and heart muscle cells were strongly stained. Islets of Langerhans, cells in CNS, prostate, soft tissues spleen and lymph node were generally negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA059144
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Breast



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ITPR2 (HGNC Symbol)

Synonyms

CFAP48, IP3R2

Description

Inositol 1,4,5-trisphosphate receptor, type 2 (HGNC Symbol)

Entrez gene summary

Chromosome

12

Cytoband

p11.23

Chromosome location (bp)

26336515 - 26833198

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000123104 (version 78.38)

Entrez gene

3709

UniProt

Q14571 (UniProt - Evidence at protein level)

neXtProt

NX_Q14571

Antibodypedia

ITPR2 antibodies


PROTEIN BROWSER

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ENST00000242737
 
ENST00000381340
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITPR2-001 ENSP00000370744
ENST00000381340
Q14571
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Show » Show » 2701 308.1 No 6
ITPR2-002 ENSP00000242737
ENST00000242737
Q14571
Show all »
Show » Show » 181 20.6 No 0