WWP1

GENE INFORMATION

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Gene name

WWP1 (HGNC Symbol)

Synonyms

AIP5, DKFZP434D2111

Description

WW domain containing E3 ubiquitin protein ligase 1 (HGNC Symbol)

Entrez gene summary

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008]

Chromosome

8 (Chromosome progress)

Cytoband

q21.3

Chromosome location (bp)

87354967 - 87490649

Ensembl

ENSG00000123124 (version 73.37)

Entrez gene

11059

UniProt

Q9H0M0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H0M0

Antibodypedia

WWP1 antibodies
 

PROTEIN VIEW

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WWP1-001
 
WWP1-006
 
WWP1-010
 
WWP1-201
 
WWP1-202
 
WWP1-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WWP1-001 ENSP00000427793
ENST00000517970
Q9H0M0
Show all »
Show » Show » 922 105.2 No 0
WWP1-006 ENSP00000429076
ENST00000520453
Show » Show » 233 27.1 No 1
WWP1-010 ENSP00000430228
ENST00000520798
H0YBS9
Show all »
Show » 55 6.2 No 0
WWP1-201 ENSP00000265428
ENST00000265428
Q9H0M0
Show all »
Show » Show » 922 105.2 No 0
WWP1-202 ENSP00000340564
ENST00000341922
Q9H0M0
Show all »
Show » Show » 792 91.5 No 0
WWP1-203 ENSP00000342665
ENST00000349423
Q9H0M0
Show all »
Show » Show » 704 81.6 No 0