Fields »

SUBCELLULAR LOCATION

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Main location(s)

Vesicles

Additional location(s)

Nucleus but not nucleoli, Centrosome 

Staining summary

Mainly localized to vesicles. In addition localized to the nucleus and centrosomes.

Reliability (APE)

Low

Antibodies in assay

HPA042629, HPA042838
 

Antibody HPA042629

 

Antibody HPA042838

 

         Cell line A-431

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Location(s)

Vesicles Vesicles 

Staining characteristics

  

Staining intensity

Moderate Weak 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Cell line U-2 OS

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Location(s)

Vesicles Vesicles 

Staining characteristics

  

Staining intensity

Weak Weak 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Nucleus but not nucleoli, Vesicles, Centrosome Vesicles 

Staining characteristics

  

Staining intensity

Moderate Weak 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in vesicles.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in vesicles.
 

Summary

Staining of vesicles in all three cell lines. Additional staining of centrosomes and the nucleus in U-251 MG.   Staining of vesicles in all three cell lines.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Centrosome
Nucleus but not nucleoli
Endosome