KCNJ2

GENE INFORMATION

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Gene name

KCNJ2 (HGNC Symbol)

Synonyms

IRK1, Kir2.1, LQT7

Description

potassium inwardly-rectifying channel, subfamily J, member 2 (HGNC Symbol)

Entrez gene summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q24.3

Chromosome location (bp)

68164814 - 68176189

Ensembl

ENSG00000123700 (version 73.37)

Entrez gene

3759

UniProt

P63252 (UniProt - Evidence at protein level)

neXtProt

NX_P63252

Antibodypedia

KCNJ2 antibodies
 

PROTEIN VIEW

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KCNJ2-001
 
KCNJ2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNJ2-001 ENSP00000441848
ENST00000535240
P63252
Show all »
Show » Show » 427 48.3 No 2
KCNJ2-002 ENSP00000243457
ENST00000243457
P63252
Show all »
Show » Show » 427 48.3 No 2