ACSL3

GENE INFORMATION

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Gene name

ACSL3 (HGNC Symbol)

Synonyms

ACS3, FACL3, PRO2194

Description

acyl-CoA synthetase long-chain family member 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q36.1

Chromosome location (bp)

223725652 - 223809357

Ensembl

ENSG00000123983 (version 73.37)

Entrez gene

2181

UniProt

O95573 (UniProt - Evidence at protein level)

neXtProt

NX_O95573

Antibodypedia

ACSL3 antibodies
 

PROTEIN VIEW

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ACSL3-001
 
ACSL3-002
 
ACSL3-003
 
ACSL3-005
 
ACSL3-007
 
ACSL3-010
 
ACSL3-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACSL3-001 ENSP00000350012
ENST00000357430
O95573
Show all »
Show » Show » 720 80.4 No 3
ACSL3-002 ENSP00000375918
ENST00000392066
O95573
Show all »
Show » Show » 720 80.4 No 3
ACSL3-003 ENSP00000416913
ENST00000413316
C9JC11
Show all »
Show » Show » 88 10.1 No 1
ACSL3-005 ENSP00000404182
ENST00000421680
H7C260
Show all »
Show » Show » 213 23.5 No 0
ACSL3-007 ENSP00000385157
ENST00000407441
Show » 179 19.9 No 0
ACSL3-010 ENSP00000438342
ENST00000535678
F5H062
Show all »
Show » Show » 95 10.9 No 1
ACSL3-012 ENSP00000441643
ENST00000540115
F5GWH2
Show all »
Show » Show » 141 15.4 No 0