NCOA3

GENE INFORMATION

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Gene name

NCOA3 (HGNC Symbol)

Synonyms

ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1

Description

nuclear receptor coactivator 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]

Chromosome

20 (Chromosome progress)

Cytoband

q13.12

Chromosome location (bp)

46130601 - 46285621

Ensembl

ENSG00000124151 (version 73.37)

Entrez gene

8202

UniProt

Q9Y6Q9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6Q9

Antibodypedia

NCOA3 antibodies
 

PROTEIN VIEW

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NCOA3-001
 
NCOA3-002
 
NCOA3-003
 
NCOA3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NCOA3-001 ENSP00000361073
ENST00000372004
Q9Y6Q9
Show all »
Show » Show » 1420 154.9 No 0
NCOA3-002 ENSP00000361065
ENST00000371997
Q9Y6Q9
Show all »
Show » Show » 1415 154.4 No 0
NCOA3-003 ENSP00000361066
ENST00000371998
Q9Y6Q9
Show all »
Show » Show » 1424 155.3 No 0
NCOA3-201 ENSP00000342123
ENST00000341724
C9JCR8
Show all »
Show » Show » 1350 147.5 No 0