PEPD

GENE INFORMATION

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Gene name

PEPD

Synonyms

Description

peptidase D (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

Chromosome

19 (Chromosome progress)

Cytoband

q13.11

Chromosome location (bp)

33877856 - 34012700

Ensembl

ENSG00000124299 (version 73.37)

Entrez gene

5184

UniProt

P12955 (UniProt - Evidence at protein level)

neXtProt

NX_P12955

Antibodypedia

PEPD antibodies
 

PROTEIN VIEW

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PEPD-001
 
PEPD-002
 
PEPD-003
 
PEPD-005
 
PEPD-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PEPD-001 ENSP00000244137
ENST00000244137
P12955
Show all »
Show » Show » 493 54.5 No 0
PEPD-002 ENSP00000380226
ENST00000397032
P12955
Show all »
Show » Show » 452 49.7 No 0
PEPD-003 ENSP00000391890
ENST00000436370
P12955
Show all »
Show » Show » 429 47.3 No 0
PEPD-005 ENSP00000467674
ENST00000593163
K7EQ51
Show all »
Show » 186 20.9 No 0
PEPD-009 ENSP00000468516
ENST00000588328
K7ES25
Show all »
Show » Show » 194 21.6 No 0