RPS10

GENERAL INFORMATION

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Gene name

RPS10

Gene description

Ribosomal protein S10

Protein class

Disease related genes
Plasma proteins
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in most tissues, except mesenchymal cells.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation. Caution, targets protein from more than one gene.

Data reliability

Supportive based on 2 antibodies.
HPA047268 , HPA048084
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Breast



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

RPS10 (HGNC Symbol)

Synonyms

MGC88819, S10

Description

Ribosomal protein S10 (HGNC Symbol)

Entrez gene summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).[provided by RefSeq, Feb 2011]

Chromosome

6

Cytoband

p21.31

Chromosome location (bp)

34417454 - 34426125

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124614 (version 78.38)

Entrez gene

6204

UniProt

P46783 (UniProt - Evidence at protein level)

neXtProt

NX_P46783

Antibodypedia

RPS10 antibodies


PROTEIN BROWSER

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ENST00000326199
 
ENST00000344700
 
ENST00000621356
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPS10-001 ENSP00000347271
ENST00000326199
P46783
Show all »
Show » Show » 165 18.9 No 0
RPS10-005 ENSP00000363169
ENST00000344700
F6U211
Show all »
Show » Show » 172 19.9 No 0
RPS10-201 ENSP00000481646
ENST00000621356
P46783
Show all »
Show » Show » 165 18.9 No 0