DEK

GENE INFORMATION

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Gene name

DEK (HGNC Symbol)

Synonyms

D6S231E

Description

DEK oncogene (HGNC Symbol)

Entrez gene summary

This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Chromosome

6 (Chromosome progress)

Cytoband

p22.3

Chromosome location (bp)

18224099 - 18265054

Ensembl

ENSG00000124795 (version 73.37)

Entrez gene

7913

UniProt

P35659 (UniProt - Evidence at protein level)

neXtProt

NX_P35659

Antibodypedia

DEK antibodies
 

PROTEIN VIEW

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DEK-001
 
DEK-002
 
DEK-003
 
DEK-005
 
DEK-006
 
DEK-007
 
DEK-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEK-001 ENSP00000380414
ENST00000397239
P35659
Show all »
Show » Show » 375 42.7 No 0
DEK-002 ENSP00000244776
ENST00000244776
P35659
Show all »
Show » Show » 341 38.7 No 0
DEK-003 ENSP00000421165
ENST00000505224
B4DFG0
Show all »
Show » Show » 347 39.5 No 0
DEK-005 ENSP00000425399
ENST00000503715
D6RDA2
Show all »
Show » Show » 122 14.2 No 0
DEK-006 ENSP00000423553
ENST00000515742
D6R9L5
Show all »
Show » 151 17.3 No 0
DEK-007 ENSP00000422380
ENST00000515770
Show » Show » 161 18.4 No 0
DEK-009 ENSP00000423427
ENST00000507591
H0Y993
Show all »
Show » Show » 156 17.8 No 0