ABCC4

GENE INFORMATION

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Gene name

ABCC4 (HGNC Symbol)

Synonyms

EST170205, MOAT-B, MOATB, MRP4

Description

ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

13 (Chromosome progress)

Cytoband

q32.1

Chromosome location (bp)

95672083 - 95953687

Ensembl

ENSG00000125257 (version 73.37)

Entrez gene

10257

UniProt

O15439 (UniProt - Evidence at protein level)

neXtProt

NX_O15439

Antibodypedia

ABCC4 antibodies
 

PROTEIN VIEW

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ABCC4-001
 
ABCC4-201
 
ABCC4-202
 
ABCC4-203
 
ABCC4-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCC4-001 ENSP00000366084
ENST00000376887
O15439
Show all »
Show » Show » 1325 149.5 No >9
ABCC4-201 ENSP00000388657
ENST00000412704
O15439
Show all »
Show » Show » 1278 144.2 No >9
ABCC4-202 ENSP00000398562
ENST00000431522
O15439
Show all »
Show » Show » 859 96.8 No >9
ABCC4-203 ENSP00000442024
ENST00000536256
B7Z3Q7
Show all »
Show » Show » 784 88.1 No 6
ABCC4-204 ENSP00000440160
ENST00000538287
Q8IUA3
Show all »
Show » 24 2.8 No 0