GRK4

GENE INFORMATION

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Gene name

GRK4 (HGNC Symbol)

Synonyms

GPRK2L, GPRK4

Description

G protein-coupled receptor kinase 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

p16.3

Chromosome location (bp)

2965335 - 3042474

Ensembl

ENSG00000125388 (version 73.37)

Entrez gene

2868

UniProt

P32298 (UniProt - Evidence at protein level)

neXtProt

NX_P32298

Antibodypedia

GRK4 antibodies
 

PROTEIN VIEW

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GRK4-001
 
GRK4-002
 
GRK4-004
 
GRK4-005
 
GRK4-012
 
GRK4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GRK4-001 ENSP00000381129
ENST00000398052
P32298
Show all »
Show » Show » 578 66.6 No 0
GRK4-002 ENSP00000381128
ENST00000398051
P32298
Show all »
Show » Show » 500 57.7 No 0
GRK4-004 ENSP00000421650
ENST00000503518
D6REW5
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84 9.2 No 0
GRK4-005 ENSP00000264764
ENST00000345167
P32298
Show all »
Show » Show » 546 63 No 0
GRK4-012 ENSP00000427445
ENST00000504933
P32298
Show all »
Show » Show » 532 61.2 No 0
GRK4-201 ENSP00000392297
ENST00000442472
B4DEC9
Show all »
134 13.3 No 0