MBOAT7

GENERAL INFORMATION

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Gene name

MBOAT7

Gene description

Membrane bound O-acyltransferase domain containing 7

Protein class

Enzymes
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cells in seminiferus ducts, adrenal gland, urothelium, adipocytes and myocytes in heart showed weak to moderate cytoplasmic positivity. Other normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA055967
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Urinary bladder

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MBOAT7 (HGNC Symbol)

Synonyms

BB1, hMBOA-7, LENG4, LPIAT

Description

Membrane bound O-acyltransferase domain containing 7 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

Chromosome

19

Cytoband

q13.42

Chromosome location (bp)

54173412 - 54189882

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125505 (version 78.38)

Entrez gene

79143

UniProt

Q96N66 (UniProt - Evidence at protein level)

neXtProt

NX_Q96N66

Antibodypedia

MBOAT7 antibodies


PROTEIN BROWSER

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ENST00000245615
 
ENST00000338624
 
ENST00000391754
 
ENST00000414665
 
ENST00000431666
 
ENST00000449249
 
ENST00000453320
 
ENST00000495279
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MBOAT7-001 ENSP00000245615
ENST00000245615
Q96N66
Show all »
Show » Show » 472 52.8 No 8
MBOAT7-002 ENSP00000375634
ENST00000391754
Q96N66
Show all »
Show » Show » 344 38.5 No 6
MBOAT7-004 ENSP00000388250
ENST00000414665
A9C4B8
Show all »
Show » Show » 256 28.6 No 5
MBOAT7-005 ENSP00000472209
ENST00000495279
Show » 181 19.8 No 3
MBOAT7-008 ENSP00000410320
ENST00000453320
C9J4E9
Show all »
Show » 170 18.5 No 1
MBOAT7-012 ENSP00000406794
ENST00000449249
H7C2M4
Show all »
Show » 123 13.3 Yes 1
MBOAT7-013 ENSP00000344377
ENST00000338624
Q96N66
Show all »
Show » Show » 399 44.7 No 5
MBOAT7-201 ENSP00000410503
ENST00000431666
Q96N66
Show all »
Show » Show » 399 44.7 No 5