INSIG2

GENE INFORMATION

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Gene name

INSIG2

Synonyms

Description

insulin induced gene 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q14.2

Chromosome location (bp)

118846028 - 118868573

Ensembl

ENSG00000125629 (version 73.37)

Entrez gene

51141

UniProt

Q9Y5U4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5U4

Antibodypedia

INSIG2 antibodies
 

PROTEIN VIEW

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INSIG2-001
 
INSIG2-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

INSIG2-001 ENSP00000245787
ENST00000245787
Q9Y5U4
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Show » Show » 225 24.8 No 6
INSIG2-007 ENSP00000400126
ENST00000411929
F8WCG8
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39 4.4 No 0