GRIA3

GENE INFORMATION

? »

Gene name

GRIA3 (HGNC Symbol)

Synonyms

GluA3, GLUR3, GLURC, MRX94

Description

glutamate receptor, ionotropic, AMPA 3 (HGNC Symbol)

Entrez gene summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]

Chromosome

X (Chromosome progress)

Cytoband

q25

Chromosome location (bp)

122318006 - 122624766

Ensembl

ENSG00000125675 (version 73.37)

Entrez gene

2892

UniProt

P42263 (UniProt - Evidence at protein level)

neXtProt

NX_P42263

Antibodypedia

GRIA3 antibodies
 

PROTEIN VIEW

? »
 
 
 
GRIA3-001
 
GRIA3-002
 
GRIA3-006
 
GRIA3-007
 
GRIA3-201
 
GRIA3-202
 
GRIA3-203
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GRIA3-001 ENSP00000360302
ENST00000371256
P42263
Show all »
Show » Show » 894 101.2 Yes 3
GRIA3-002 ENSP00000360297
ENST00000371251
P42263
Show all »
Show » Show » 894 101.2 Yes 3
GRIA3-006 ENSP00000360311
ENST00000371264
Q4TT43
Show all »
Show » 164 18.1 Yes 0
GRIA3-007 ENSP00000360313
ENST00000371266
Q4TT43
Show all »
Show » 164 18.1 Yes 0
GRIA3-201 ENSP00000264357
ENST00000264357
P42263
Show all »
Show » Show » 894 101.2 Yes 3
GRIA3-202 ENSP00000446440
ENST00000541091
B7Z4C0
Show all »
Show » Show » 662 76.2 No 2
GRIA3-203 ENSP00000446146
ENST00000542149
F5H470
Show all »
Show » Show » 824 93.4 Yes 2