ATG4C

GENE INFORMATION

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Gene name

ATG4C (HGNC Symbol)

Synonyms

APG4C, AUTL1, AUTL3, FLJ14867

Description

autophagy related 4C, cysteine peptidase (HGNC Symbol)

Entrez gene summary

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p31.3

Chromosome location (bp)

63249806 - 63331184

Ensembl

ENSG00000125703 (version 73.37)

Entrez gene

84938

UniProt

Q96DT6 (UniProt - Evidence at protein level)

neXtProt

NX_Q96DT6

Antibodypedia

ATG4C antibodies
 

PROTEIN VIEW

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ATG4C-001
 
ATG4C-002
 
ATG4C-003
 
ATG4C-004
 
ATG4C-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATG4C-001 ENSP00000322159
ENST00000317868
Q96DT6
Show all »
Show » Show » 458 52.5 No 0
ATG4C-002 ENSP00000360161
ENST00000371120
Q96DT6
Show all »
Show » Show » 458 52.5 No 0
ATG4C-003 ENSP00000396614
ENST00000443289
C9JC51
Show all »
Show » 151 17.4 No 0
ATG4C-004 ENSP00000360159
ENST00000371118
A6NGQ4
Show all »
Show » 189 21.7 No 0
ATG4C-005 ENSP00000391820
ENST00000414558
110 12.2 No 0