SH2D3A

GENERAL INFORMATION

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Gene name

SH2D3A

Gene description

SH2 domain containing 3A

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues showed moderate cytoplasmic staining. Strong staining was observed in several tissues e.g. the gastrointestinal tract, breast and smooth muscle. Nuclear positivity was observed in neurons. Pancreatic islets, glial cells and lymphoid tissues were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA035722
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

SH2D3A (HGNC Symbol)

Synonyms

NSP1

Description

SH2 domain containing 3A (HGNC Symbol)

Entrez gene summary

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

6752160 - 6767588

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125731 (version 78.38)

Entrez gene

10045

UniProt

Q9BRG2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BRG2

Antibodypedia

SH2D3A antibodies


PROTEIN BROWSER

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ENST00000245908
 
ENST00000437152
 
ENST00000597687
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SH2D3A-001 ENSP00000245908
ENST00000245908
Q9BRG2
Show all »
Show » Show » 576 63.1 No 0
SH2D3A-004 ENSP00000393303
ENST00000437152
Q9BRG2
Show all »
Show » Show » 483 52.4 No 0
SH2D3A-007 ENSP00000470700
ENST00000597687
M0QZQ6
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Show » 238 25.9 No 0