GPR108

GENE INFORMATION

? »

Gene name

GPR108 (HGNC Symbol)

Synonyms

LUSTR2

Description

G protein-coupled receptor 108 (HGNC Symbol)

Entrez gene summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

6729925 - 6737614

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125734 (version 75.37)

Entrez gene

102465474

UniProt

Q9NPR9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9NPR9

Antibodypedia

GPR108 antibodies
 

PROTEIN VIEW

? »
 
 
 
GPR108-001
 
GPR108-002
 
GPR108-003
 
GPR108-005
 
GPR108-007
 
GPR108-011
 
GPR108-013
 
GPR108-014
 
GPR108-016
 
GPR108-017
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPR108-001 ENSP00000264080
ENST00000264080
Q9NPR9
Show all »
Show » Show » 543 60.6 No 8
GPR108-002 ENSP00000401284
ENST00000430424
G5E9L6
Show all »
Show » Show » 301 34.3 No 8
GPR108-003 ENSP00000470844
ENST00000595908
Show » 103 11.4 No 0
GPR108-005 ENSP00000469797
ENST00000601716
Show » 224 24.3 No 0
GPR108-007 ENSP00000470197
ENST00000597298
M0QZ03
Show all »
Show » Show » 36 4.1 No 1
GPR108-011 ENSP00000470823
ENST00000594034
M0QZW9
Show all »
Show » Show » 177 20.2 No 3
GPR108-013 ENSP00000472496
ENST00000594500
M0R2E1
Show all »
Show » Show » 167 18.9 No 2
GPR108-014 ENSP00000471846
ENST00000597706
M0QZ03
Show all »
Show » Show » 331 36.5 Yes 2
GPR108-016 ENSP00000472048
ENST00000598052
Show » 145 15.6 Yes 0
GPR108-017 ENSP00000473228
ENST00000598955
Show » Show » 194 21.9 No 4