SYMPK

GENE INFORMATION

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Gene name

SYMPK (HGNC Symbol)

Synonyms

SPK, SYM

Description

symplekin (HGNC Symbol)

Entrez gene summary

This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.32

Chromosome location (bp)

46318668 - 46366548

Ensembl

ENSG00000125755 (version 73.37)

Entrez gene

8189

UniProt

Q92797 (UniProt - Evidence at protein level)

neXtProt

NX_Q92797

Antibodypedia

SYMPK antibodies
 

PROTEIN VIEW

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SYMPK-001
 
SYMPK-006
 
SYMPK-011
 
SYMPK-012
 
SYMPK-014
 
SYMPK-019
 
SYMPK-021
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SYMPK-001 ENSP00000245934
ENST00000245934
Q92797
Show all »
Show » Show » 1274 141.1 No 0
SYMPK-006 ENSP00000473136
ENST00000600237
M0R3C7
Show all »
Show » Show » 673 74.5 No 0
SYMPK-011 ENSP00000471770
ENST00000594293
M0R1C2
Show all »
Show » 115 12.7 No 0
SYMPK-012 ENSP00000471694
ENST00000598059
M0R180
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Show » 137 15.3 No 0
SYMPK-014 ENSP00000470977
ENST00000601600
M0R039
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50 5.2 No 0
SYMPK-019 ENSP00000470957
ENST00000596824
95 10.8 No 0
SYMPK-021 ENSP00000469296
ENST00000602061
M0QXP5
Show all »
Show » 142 15.8 No 0