TGM3

GENERAL INFORMATION

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Gene name

TGM3

Gene description

Transglutaminase 3

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (esophagus)
GTEx:Tissue enriched (esophagus)

Protein evidence

Evidence at protein level

Protein localization

External data suggests expression in hair follicle. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

No internal RNA expression data available for correlation. Pending additional tissue.

Data reliability

Uncertain based on 1 antibody.
HPA004728
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Esophagus

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (esophagus)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (esophagus)

Organ

Expression



GENE INFORMATION

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Gene name

TGM3 (HGNC Symbol)

Synonyms

TGE

Description

Transglutaminase 3 (HGNC Symbol)

Entrez gene summary

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

2296001 - 2341078

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125780 (version 78.38)

Entrez gene

7053

UniProt

Q08188 (UniProt - Evidence at protein level)

neXtProt

NX_Q08188

Antibodypedia

TGM3 antibodies


PROTEIN BROWSER

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ENST00000381458
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TGM3-001 ENSP00000370867
ENST00000381458
Q08188
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