MAX

GENE INFORMATION

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Gene name

MAX (HGNC Symbol)

Synonyms

bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8

Description

MYC associated factor X (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Chromosome

14 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

65472892 - 65569413

Ensembl

ENSG00000125952 (version 73.37)

Entrez gene

4149

UniProt

P61244 (UniProt - Evidence at protein level)

neXtProt

NX_P61244

Antibodypedia

MAX antibodies
 

PROTEIN VIEW

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MAX-001
 
MAX-002
 
MAX-003
 
MAX-004
 
MAX-005
 
MAX-006
 
MAX-007
 
MAX-008
 
MAX-010
 
MAX-011
 
MAX-012
 
MAX-013
 
MAX-014
 
MAX-017
 
MAX-018
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAX-001 ENSP00000351175
ENST00000358402
P61244
Show all »
Show » Show » 151 17.2 No 0
MAX-002 ENSP00000351490
ENST00000358664
P61244
Show all »
Show » Show » 160 18.3 No 0
MAX-003 ENSP00000342482
ENST00000341653
A6NH73
Show all »
Show » Show » 83 9.6 No 0
MAX-004 ENSP00000284165
ENST00000284165
P61244
Show all »
Show » Show » 134 15.4 No 0
MAX-005 ENSP00000246163
ENST00000246163
P61244
Show all »
Show » Show » 96 11.5 No 0
MAX-006 ENSP00000452378
ENST00000556979
P61244
Show all »
Show » Show » 103 12.1 No 0
MAX-007 ENSP00000451907
ENST00000553928
P61244
Show all »
Show » Show » 103 12.1 No 0
MAX-008 ENSP00000378104
ENST00000394606
P61244
Show all »
Show » Show » 103 12.1 No 0
MAX-010 ENSP00000452286
ENST00000555667
Q6V3B1
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Show » 94 11 No 0
MAX-011 ENSP00000450763
ENST00000555932
G3V2N4
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82 8.7 No 0
MAX-012 ENSP00000452405
ENST00000555419
G3V5L1
Show all »
Show » Show » 124 14.1 No 0
MAX-013 ENSP00000452197
ENST00000557746
G3V563
Show all »
Show » 121 14 No 0
MAX-014 ENSP00000450818
ENST00000556443
G3V2R5
Show all »
Show » 125 14.3 No 0
MAX-017 ENSP00000452206
ENST00000556892
G3V570
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Show » Show » 44 5.2 No 0
MAX-018 ENSP00000450955
ENST00000557277
G3V302
Show all »
97 10.7 No 0