CCR7

GENE INFORMATION

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Gene name

CCR7 (HGNC Symbol)

Synonyms

BLR2, CD197, CDw197, CMKBR7, EBI1

Description

Chemokine (C-C motif) receptor 7 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.2

Chromosome location (bp)

38710021 - 38721724

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000126353 (version 75.37)

Entrez gene

1236

UniProt

P32248 (UniProt - Evidence at protein level)

neXtProt

NX_P32248

Antibodypedia

CCR7 antibodies
 

PROTEIN VIEW

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CCR7-001
 
CCR7-002
 
CCR7-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCR7-001 ENSP00000246657
ENST00000246657
P32248
Show all »
Show » Show » 378 42.9 Yes 7
CCR7-002 ENSP00000462631
ENST00000579344
J3KSS9
Show all »
Show » Show » 372 42.2 Yes 7
CCR7-003 ENSP00000463075
ENST00000578085
J3KTN5
Show all »
Show » Show » 199 22.6 No 5