PRDX5

GENE INFORMATION

? »

Gene name

PRDX5 (HGNC Symbol)

Synonyms

ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10

Description

peroxiredoxin 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

q13.1

Chromosome location (bp)

64085560 - 64089283

Ensembl

ENSG00000126432 (version 73.37)

Entrez gene

25824

UniProt

P30044 (UniProt - Evidence at protein level)

neXtProt

NX_P30044

Antibodypedia

PRDX5 antibodies
 

PROTEIN VIEW

? »
 
 
 
PRDX5-001
 
PRDX5-002
 
PRDX5-003
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRDX5-001 ENSP00000265462
ENST00000265462
P30044
Show all »
Show » Show » 214 22.1 No 0
PRDX5-002 ENSP00000335334
ENST00000352435
P30044
Show all »
Show » Show » 170 17.5 No 0
PRDX5-003 ENSP00000335363
ENST00000347941
P30044
Show all »
Show » Show » 125 12.9 No 0