IRF3

GENE INFORMATION

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Gene name

IRF3

Synonyms

Description

interferon regulatory factor 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Chromosome

19 (Chromosome progress)

Cytoband

q13.33

Chromosome location (bp)

50162826 - 50169132

Ensembl

ENSG00000126456 (version 73.37)

Entrez gene

3661

UniProt

Q14653 (UniProt - Evidence at protein level)

neXtProt

NX_Q14653

Antibodypedia

IRF3 antibodies
 

PROTEIN VIEW

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 « 
 
IRF3-001
 
IRF3-002
 
IRF3-003
 
IRF3-004
 
IRF3-005
 
IRF3-006
 
IRF3-007
 
IRF3-008
 
IRF3-009
 
IRF3-010
 
IRF3-011
 
IRF3-012
 
IRF3-017
 
IRF3-019
 
IRF3-020
 
IRF3-022
 
IRF3-023
 
IRF3-024
 
IRF3-025
 
IRF3-026
 
IRF3-027
 
IRF3-028
 
IRF3-201
 
IRF3-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IRF3-001 ENSP00000366344
ENST00000377139
Q14653
Show all »
Show » Show » 427 47.2 No 0
IRF3-002 ENSP00000471896
ENST00000601291
Q14653
Show all »
Show » Show » 452 49.1 No 0
IRF3-003 ENSP00000470436
ENST00000597636
M0QZB8
Show all »
Show » Show » 329 36.3 No 0
IRF3-004 ENSP00000469113
ENST00000597198
Q14653
Show all »
Show » Show » 427 47.2 No 0
IRF3-005 ENSP00000471358
ENST00000599223
Q14653
Show all »
Show » Show » 300 33.2 No 0
IRF3-006 ENSP00000310127
ENST00000309877
Q14653
Show all »
Show » Show » 427 47.2 No 0
IRF3-007 ENSP00000470431
ENST00000600911
M0QZB7
Show all »
Show » Show » 408 44.5 No 0
IRF3-008 ENSP00000470512
ENST00000596765
Q14653
Show all »
Show » Show » 154 16.7 No 0
IRF3-009 ENSP00000470069
ENST00000599144
M0QYT9
Show all »
Show » Show » 281 30.8 No 0
IRF3-010 ENSP00000472582
ENST00000598808
M0QYT9
Show all »
Show » Show » 281 30.8 No 0
IRF3-011 ENSP00000472601
ENST00000593922
M0QYT9
Show all »
Show » Show » 281 30.8 No 0
IRF3-012 ENSP00000472700
ENST00000600022
Show » 154 16.7 No 0
IRF3-017 ENSP00000468911
ENST00000596822
M0QX56
Show all »
135 14 No 0
IRF3-019 ENSP00000470140
ENST00000601809
M0QYX3
Show all »
Show » Show » 191 21.1 No 0
IRF3-020 ENSP00000470905
ENST00000600453
M0R007
Show all »
Show » Show » 102 11.8 No 0
IRF3-022 ENSP00000471517
ENST00000593818
M0R0X9
Show all »
Show » Show » 106 11.5 No 0
IRF3-023 ENSP00000469067
ENST00000595034
M0QXC8
Show all »
Show » Show » 119 13 No 0
IRF3-024 ENSP00000471402
ENST00000601373
M0R0R8
Show all »
Show » Show » 84 9.2 No 0
IRF3-025 ENSP00000473128
ENST00000596756
M0R3C2
Show all »
Show » Show » 264 29.2 No 0
IRF3-026 ENSP00000473232
ENST00000596788
71 7.6 No 0
IRF3-027 ENSP00000473176
ENST00000593337
M0R3E9
Show all »
Show » Show » 153 17.4 No 0
IRF3-028 ENSP00000472223
ENST00000598108
M0R205
Show all »
Show » Show » 287 31.8 No 0
IRF3-201 ENSP00000366339
ENST00000377135
Q14653
Show all »
Show » Show » 300 33.2 No 0
IRF3-202 ENSP00000400378
ENST00000442265
Q5FBY4
Show all »
Show » Show » 104 12.3 No 0