DACH2

GENE INFORMATION

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Gene name

DACH2

Synonyms

Description

Dachshund family transcription factor 2 (HGNC Symbol)

Entrez gene summary

This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Chromosome

X

Cytoband

q21.2

Chromosome location (bp)

86148458 - 86832604

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000126733 (version 78.38)

Entrez gene

117154

UniProt

Q96NX9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96NX9

Antibodypedia

DACH2 antibodies
 

PROTEIN VIEW

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DACH2-001
 
DACH2-002
 
DACH2-004
 
DACH2-006
 
DACH2-007
 
DACH2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DACH2-001 ENSP00000362223
ENST00000373131
Q96NX9
Show all »
Show » Show » 571 61.9 No 0
DACH2-002 ENSP00000421919
ENST00000510272
Q96NX9
Show all »
Show » Show » 380 41.8 No 0
DACH2-004 ENSP00000422727
ENST00000484479
H0Y912
Show all »
Show » 249 27.8 No 0
DACH2-006 ENSP00000420896
ENST00000508860
Q96NX9
Show all »
Show » Show » 432 47.2 No 0
DACH2-007 ENSP00000362217
ENST00000373125
Q96NX9
Show all »
Show » Show » 599 65.3 No 0
DACH2-201 ENSP00000478116
ENST00000613770
Show » 427 46.5 No 0