DACH2

GENE INFORMATION

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Gene name

DACH2

Synonyms

Description

Dachshund homolog 2 (Drosophila) (HGNC Symbol)

Entrez gene summary

This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Chromosome

X

Cytoband

q21.2

Chromosome location (bp)

85403462 - 86087607

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000126733 (version 75.37)

Entrez gene

117154

UniProt

Q96NX9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96NX9

Antibodypedia

DACH2 antibodies
 

PROTEIN VIEW

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DACH2-001
 
DACH2-002
 
DACH2-003
 
DACH2-004
 
DACH2-006
 
DACH2-007
 
DACH2-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DACH2-001 ENSP00000362223
ENST00000373131
Q96NX9
Show all »
Show » 571 61.9 No 0
DACH2-002 ENSP00000421919
ENST00000510272
Q96NX9
Show all »
Show » 380 41.8 No 0
DACH2-003 ENSP00000421509
ENST00000461604
D6RFG7
Show all »
Show » 440 47.3 No 0
DACH2-004 ENSP00000422727
ENST00000484479
H0Y912
Show all »
249 27.8 No 0
DACH2-006 ENSP00000420896
ENST00000508860
Q96NX9
Show all »
Show » 432 47.2 No 0
DACH2-007 ENSP00000362217
ENST00000373125
Q96NX9
Show all »
Show » 599 65.3 No 0
DACH2-008 ENSP00000426837
ENST00000506327
D6REJ4
Show all »
Show » 175 18.7 No 0