HNRNPH2

GENE INFORMATION

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Gene name

HNRNPH2 (HGNC Symbol)

Synonyms

FTP3, hnRNPH', HNRPH', HNRPH2

Description

heterogeneous nuclear ribonucleoprotein H2 (H') (HGNC Symbol)

Entrez gene summary

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011]

Chromosome

X (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

100663283 - 100669121

Ensembl

ENSG00000126945 (version 73.37)

Entrez gene

3188

UniProt

P55795 (UniProt - Evidence at protein level)

neXtProt

NX_P55795

Antibodypedia

HNRNPH2 antibodies
 

PROTEIN VIEW

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HNRNPH2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HNRNPH2-001 ENSP00000361927
ENST00000316594
P55795
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