BCL11B

GENE INFORMATION

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Gene name

BCL11B (HGNC Symbol)

Synonyms

CTIP-2, CTIP2, hRIT1-alpha, ZNF856B

Description

B-cell CLL/lymphoma 11B (zinc finger protein) (HGNC Symbol)

Entrez gene summary

This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

Chromosome

14 (Chromosome progress)

Cytoband

q32.2

Chromosome location (bp)

99635624 - 99737861

Ensembl

ENSG00000127152 (version 73.37)

Entrez gene

64919

UniProt

Q9C0K0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9C0K0

Antibodypedia

BCL11B antibodies
 

PROTEIN VIEW

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BCL11B-001
 
BCL11B-002
 
BCL11B-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BCL11B-001 ENSP00000349723
ENST00000357195
Q9C0K0
Show all »
Show » Show » 894 95.5 No 0
BCL11B-002 ENSP00000280435
ENST00000345514
Q9C0K0
Show all »
Show » Show » 823 88.5 No 0
BCL11B-003 ENSP00000387419
ENST00000443726
D3YTK1
Show all »
Show » Show » 700 75.4 No 0