DYRK2

GENE INFORMATION

? »

Gene name

DYRK2

Synonyms

Description

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (HGNC Symbol)

Entrez gene summary

DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008]

Chromosome

12 (Chromosome progress)

Cytoband

q15

Chromosome location (bp)

68042118 - 68059186

Ensembl

ENSG00000127334 (version 73.37)

Entrez gene

8445

UniProt

Q92630 (UniProt - Evidence at protein level)

neXtProt

NX_Q92630

Antibodypedia

DYRK2 antibodies
 

PROTEIN VIEW

? »
 
 
 
DYRK2-001
 
DYRK2-002
 
DYRK2-003
 
DYRK2-005
 
DYRK2-006
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DYRK2-001 ENSP00000342105
ENST00000344096
Q92630
Show all »
Show » Show » 601 66.7 No 0
DYRK2-002 ENSP00000377186
ENST00000393555
Q92630
Show all »
Show » Show » 528 59.7 No 0
DYRK2-003 ENSP00000440839
ENST00000543747
F5GXG1
Show all »
Show » 156 17.4 No 0
DYRK2-005 ENSP00000324733
ENST00000319833
G8JLB4
Show all »
Show » 94 10.4 No 0
DYRK2-006 ENSP00000443314
ENST00000542503
F5H5L5
Show all »
Show » Show » 167 18.9 Yes 1