Fields »

SUBCELLULAR LOCATION

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Main location(s)

Plasma membrane, Cytoplasm

Additional location(s)

Mitochondria 

Staining summary

Mainly localized to the cytoplasm and plasma membrane. In addition localized to mitochondria.

Reliability (APE)

Low

Antibodies in assay

HPA039534, HPA041207
 

Antibody HPA039534

 

Antibody HPA041207

 

         Cell line A-431

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Location(s)

Plasma membrane, Cytoplasm, Mitochondria   

Staining characteristics

   

Staining intensity

Strong   

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
   

Comment

   

         Cell line U-2 OS

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Location(s)

Plasma membrane, Cytoplasm, Mitochondria  

Staining characteristics

  

Staining intensity

Strong Negative 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Plasma membrane, Cytoplasm  

Staining characteristics

  

Staining intensity

Strong Negative 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in plasma membrane, cytoplasm & mitochondria.
 

Immunofluorescent staining of human cell line U-2 OS shows no positivity.
 

Summary

Staining of cytoplasm and plasma membrane in all three cell lines with additional staining of mitochondria in A-431 and U-2 OS.   No staining was observed in any of the three cell lines.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Cytoplasm
Mitochondria
Plasma membrane