RNF6

GENE INFORMATION

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Gene name

RNF6 (HGNC Symbol)

Synonyms

DKFZp686P0776

Description

ring finger protein (C3H2C3 type) 6 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008]

Chromosome

13 (Chromosome progress)

Cytoband

q12.13

Chromosome location (bp)

26706253 - 26796791

Ensembl

ENSG00000127870 (version 73.37)

Entrez gene

6049

UniProt

Q9Y252 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y252

Antibodypedia

RNF6 antibodies
 

PROTEIN VIEW

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RNF6-001
 
RNF6-002
 
RNF6-006
 
RNF6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RNF6-001 ENSP00000342121
ENST00000346166
Q9Y252
Show all »
Show » 685 78.1 No 0
RNF6-002 ENSP00000370982
ENST00000381570
Q9Y252
Show all »
Show » 685 78.1 No 0
RNF6-006 ENSP00000371000
ENST00000381588
Q9Y252
Show all »
Show » 685 78.1 No 0
RNF6-201 ENSP00000382665
ENST00000399762
B4DDP0
Show all »
Show » 329 37.1 No 0