MCHR1

GENERAL INFORMATION

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Gene name

MCHR1

Gene description

Melanin-concentrating hormone receptor 1

Protein class

G-protein coupled receptors
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (cerebral cortex)
GTEx:Tissue enhanced (cerebral cortex, endometrium)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, endometrium)

Organ

Expression



GENE INFORMATION

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Gene name

MCHR1 (HGNC Symbol)

Synonyms

GPR24, MCH1R, SLC1

Description

Melanin-concentrating hormone receptor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin. [provided by RefSeq, Jul 2008]

Chromosome

22

Cytoband

q13.2

Chromosome location (bp)

40678750 - 40682814

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128285 (version 78.38)

Entrez gene

2847

UniProt

Q99705 (UniProt - Evidence at protein level)

neXtProt

NX_Q99705

Antibodypedia

MCHR1 antibodies


PROTEIN BROWSER

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ENST00000249016
 
ENST00000381433
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MCHR1-001 ENSP00000249016
ENST00000249016
Q99705
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Show » Show » 422 46 No 7
MCHR1-003 ENSP00000370841
ENST00000381433
A6ZJ87
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Show » Show » 296 31.9 No 4