PODXL

GENE INFORMATION

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Gene name

PODXL (HGNC Symbol)

Synonyms

Gp200, PC, PCLP

Description

podocalyxin-like (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q32.3

Chromosome location (bp)

131185021 - 131242976

Ensembl

ENSG00000128567 (version 73.37)

Entrez gene

5420

UniProt

O00592 (UniProt - Evidence at protein level)

neXtProt

NX_O00592

Antibodypedia

PODXL antibodies
 

PROTEIN VIEW

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PODXL-001
 
PODXL-003
 
PODXL-005
 
PODXL-201
 
PODXL-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PODXL-001 ENSP00000319782
ENST00000322985
O00592
Show all »
Show » Show » 526 55.4 Yes 1
PODXL-003 ENSP00000390152
ENST00000446198
G3V0E6
Show all »
324 32.7 Yes 0
PODXL-005 ENSP00000367817
ENST00000378555
O00592
Show all »
Show » Show » 558 58.6 Yes 1
PODXL-201 ENSP00000442655
ENST00000537928
F5H7A2
Show all »
Show » 526 55.3 Yes 1
PODXL-202 ENSP00000440518
ENST00000541194
F5GWY5
Show all »
Show » 560 58.9 Yes 1