ALDH1A2

GENE INFORMATION

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Gene name

ALDH1A2 (HGNC Symbol)

Synonyms

RALDH2

Description

aldehyde dehydrogenase 1 family, member A2 (HGNC Symbol)

Entrez gene summary

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]

Chromosome

15 (Chromosome progress)

Cytoband

q21.3

Chromosome location (bp)

58245622 - 58790065

Ensembl

ENSG00000128918 (version 73.37)

Entrez gene

8854

UniProt

O94788 (UniProt - Evidence at protein level)

neXtProt

NX_O94788

Antibodypedia

ALDH1A2 antibodies
 

PROTEIN VIEW

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ALDH1A2-001
 
ALDH1A2-002
 
ALDH1A2-003
 
ALDH1A2-015
 
ALDH1A2-016
 
ALDH1A2-017
 
ALDH1A2-021
 
ALDH1A2-023
 
ALDH1A2-024
 
ALDH1A2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALDH1A2-001 ENSP00000249750
ENST00000249750
O94788
Show all »
Show » Show » 518 56.7 No 0
ALDH1A2-002 ENSP00000309623
ENST00000347587
O94788
Show all »
Show » Show » 480 53.1 No 0
ALDH1A2-003 ENSP00000453292
ENST00000558239
Q9UED3
Show all »
Show » 25 2.8 No 0
ALDH1A2-015 ENSP00000416754
ENST00000430119
E9PF31
Show all »
40 4.3 No 0
ALDH1A2-016 ENSP00000453600
ENST00000558231
H0YMG7
Show all »
Show » Show » 489 53.8 No 0
ALDH1A2-017 ENSP00000453408
ENST00000559517
O94788
Show all »
Show » Show » 422 46.1 No 0
ALDH1A2-021 ENSP00000452850
ENST00000561070
H0YKL3
Show all »
Show » 85 9.6 No 0
ALDH1A2-023 ENSP00000453734
ENST00000558384
24 2.6 No 0
ALDH1A2-024 ENSP00000454028
ENST00000557967
9 1 No 0
ALDH1A2-201 ENSP00000438296
ENST00000537372
O94788
Show all »
Show » Show » 497 54.7 No 0