IVD

GENE INFORMATION

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Gene name

IVD (HGNC Symbol)

Synonyms

ACAD2

Description

isovaleryl-CoA dehydrogenase (HGNC Symbol)

Entrez gene summary

Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

Chromosome

15 (Chromosome progress)

Cytoband

q15.1

Chromosome location (bp)

40697686 - 40728146

Ensembl

ENSG00000128928 (version 73.37)

Entrez gene

3712

UniProt

P26440 (UniProt - Evidence at protein level)

neXtProt

NX_P26440

Antibodypedia

IVD antibodies
 

PROTEIN VIEW

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IVD-001
 
IVD-002
 
IVD-006
 
IVD-008
 
IVD-009
 
IVD-010
 
IVD-012
 
IVD-013
 
IVD-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IVD-001 ENSP00000418397
ENST00000487418
J3KR54
Show all »
Show » Show » 426 46.7 No 0
IVD-002 ENSP00000417990
ENST00000479013
P26440
Show all »
Show » Show » 396 43.1 No 0
IVD-006 ENSP00000417256
ENST00000473112
Show » Show » 307 32.8 No 0
IVD-008 ENSP00000454145
ENST00000466756
58 6.2 No 0
IVD-009 ENSP00000453146
ENST00000491554
H0YLC3
Show all »
Show » Show » 243 26.4 No 0
IVD-010 ENSP00000452949
ENST00000481262
Show » 145 15.7 No 0
IVD-012 ENSP00000453929
ENST00000559575
41 4.1 No 0
IVD-013 ENSP00000453821
ENST00000558610
H0YN10
Show all »
Show » 212 23.4 No 0
IVD-201 ENSP00000249760
ENST00000249760
P26440
Show all »
Show » Show » 423 46.3 No 0