ATP1B2

GENE INFORMATION

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Gene name

ATP1B2 (HGNC Symbol)

Synonyms

AMOG

Description

ATPase, Na+/K+ transporting, beta 2 polypeptide (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p13.1

Chromosome location (bp)

7549945 - 7561086

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129244 (version 75.37)

Entrez gene

482

UniProt

P14415 (UniProt - Evidence at protein level)

neXtProt

NX_P14415

Antibodypedia

ATP1B2 antibodies
 

PROTEIN VIEW

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ATP1B2-001
 
ATP1B2-002
 
ATP1B2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP1B2-001 ENSP00000250111
ENST00000250111
P14415
Show all »
Show » Show » 290 33.4 No 1
ATP1B2-002 ENSP00000459145
ENST00000577026
I3L1V9
Show all »
Show » Show » 167 19.1 No 0
ATP1B2-003 ENSP00000460499
ENST00000577113
Show » Show » 172 19.3 No 0