RIPK3

GENE INFORMATION

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Gene name

RIPK3 (HGNC Symbol)

Synonyms

RIP3

Description

receptor-interacting serine-threonine kinase 3 (HGNC Symbol)

Entrez gene summary

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]

Chromosome

14 (Chromosome progress)

Cytoband

q12

Chromosome location (bp)

24805227 - 24809251

Ensembl

ENSG00000129465 (version 73.37)

Entrez gene

11035

UniProt

Q9Y572 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y572

Antibodypedia

RIPK3 antibodies
 

PROTEIN VIEW

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RIPK3-001
 
RIPK3-002
 
RIPK3-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RIPK3-001 ENSP00000216274
ENST00000216274
Q9Y572
Show all »
Show » Show » 518 56.9 No 0
RIPK3-002 ENSP00000452328
ENST00000554756
Q9Y572
Show all »
Show » Show » 231 25.3 No 0
RIPK3-009 ENSP00000451840
ENST00000554569
162 17.6 No 0