LPPR3

GENERAL INFORMATION

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Gene name

LPPR3

Gene description

Lipid phosphate phosphatase-related protein type 3

Protein class

Enzymes
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (bone marrow, cerebral cortex, fallopian tube)
GTEx:Group enriched (cerebral cortex, fallopian tube, hippocampus, testis)

Protein evidence

Evidence at protein level

Protein localization

Nuclear/nucleolar expression in several tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA052293 , HPA057034
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (bone marrow, cerebral cortex, fallopian tube)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebral cortex, fallopian tube, hippocampus, testis)

Organ

Expression



GENE INFORMATION

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Gene name

LPPR3

Synonyms

Description

Lipid phosphate phosphatase-related protein type 3 (UniProtKB/Swiss-Prot)

Entrez gene summary

The proteins in the lipid phosphate phosphatase (LPP) family, including PRG2, are integral membrane proteins that modulate bioactive lipid phosphates including phosphatidate, lysophosphatidate, and sphingosine-1-phosphate in the context of cell migration, neurite retraction, and mitogenesis (Brauer et al., 2003 [PubMed 12730698]).[supplied by OMIM, Mar 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

812488 - 821977

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129951 (version 78.38)

Entrez gene

79948

UniProt

Q6T4P5 (UniProt - Evidence at transcript level)

neXtProt

NX_Q6T4P5

Antibodypedia

LPPR3 antibodies


PROTEIN BROWSER

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ENST00000359894
 
ENST00000517665
 
ENST00000519502
 
ENST00000520876
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LPPR3-001 ENSP00000430297
ENST00000520876
Q6T4P5
Show all »
Show » Show » 718 76 No 6
LPPR3-002 ENSP00000352962
ENST00000359894
K7ELK5
Show all »
Show » Show » 746 78.9 No 5
LPPR3-003 ENSP00000466122
ENST00000519502
Show » 129 14.2 No 2
LPPR3-005 ENSP00000430544
ENST00000517665
Show » Show » 120 12.6 No 1