CBFA2T3

GENE INFORMATION

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Gene name

CBFA2T3 (HGNC Symbol)

Synonyms

MTG16, MTGR2, ZMYND4

Description

core-binding factor, runt domain, alpha subunit 2; translocated to, 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]

Chromosome

16 (Chromosome progress)

Cytoband

q24.3

Chromosome location (bp)

88941266 - 89043612

Ensembl

ENSG00000129993 (version 73.37)

Entrez gene

863

UniProt

O75081 (UniProt - Evidence at protein level)

neXtProt

NX_O75081

Antibodypedia

CBFA2T3 antibodies
 

PROTEIN VIEW

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 « 
 
CBFA2T3-001
 
CBFA2T3-002
 
CBFA2T3-006
 
CBFA2T3-007
 
CBFA2T3-008
 
CBFA2T3-009
 
CBFA2T3-010
 
CBFA2T3-011
 
CBFA2T3-012
 
CBFA2T3-201
 
CBFA2T3-202
 
CBFA2T3-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CBFA2T3-001 ENSP00000268679
ENST00000268679
O75081
Show all »
Show » Show » 653 71.2 No 0
CBFA2T3-002 ENSP00000332122
ENST00000327483
O75081
Show all »
Show » Show » 567 62.4 No 0
CBFA2T3-006 ENSP00000454851
ENST00000569464
H3BNH2
Show all »
Show » Show » 419 46.7 No 0
CBFA2T3-007 ENSP00000464125
ENST00000566868
Show » 34 3.5 No 0
CBFA2T3-008 ENSP00000456717
ENST00000562719
H3BSI4
Show all »
Show » Show » 132 13.8 No 0
CBFA2T3-009 ENSP00000454872
ENST00000563640
H3BNI7
Show all »
Show » Show » 130 12.9 No 0
CBFA2T3-010 ENSP00000457410
ENST00000569443
H3BU07
Show all »
Show » Show » 121 12.5 No 0
CBFA2T3-011 ENSP00000454609
ENST00000564416
H3BMZ0
Show all »
Show » Show » 62 6.7 No 0
CBFA2T3-012 ENSP00000456102
ENST00000570046
H3BR72
Show all »
Show » Show » 22 2.3 No 0
CBFA2T3-201 ENSP00000353449
ENST00000360302
O75081
Show all »
Show » Show » 567 62.4 No 0
CBFA2T3-202 ENSP00000395739
ENST00000436887
E7EU24
Show all »
Show » Show » 615 66.9 No 0
CBFA2T3-203 ENSP00000401254
ENST00000448839
O75081
Show all »
Show » Show » 577 63.1 No 0