DPP6

GENE INFORMATION

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Gene name

DPP6 (HGNC Symbol)

Synonyms

DPPX

Description

dipeptidyl-peptidase 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q36.2

Chromosome location (bp)

153584182 - 154685995

Ensembl

ENSG00000130226 (version 73.37)

Entrez gene

1804

UniProt

P42658 (UniProt - Evidence at protein level)

neXtProt

NX_P42658

Antibodypedia

DPP6 antibodies
 

PROTEIN VIEW

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DPP6-001
 
DPP6-002
 
DPP6-003
 
DPP6-006
 
DPP6-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DPP6-001 ENSP00000385578
ENST00000404039
E9PF59
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Show » Show » 801 91.2 No 1
DPP6-002 ENSP00000384393
ENST00000406326
Q8IYG9
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Show » 353 38.7 No 1
DPP6-003 ENSP00000367001
ENST00000377770
P42658
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Show » Show » 865 97.6 No 1
DPP6-006 ENSP00000328226
ENST00000332007
P42658
Show all »
Show » Show » 803 91.3 No 1
DPP6-007 ENSP00000397303
ENST00000427557
E9PDL2
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Show » Show » 758 86.3 No 1