ACE2

GENE INFORMATION

? »

Gene name

ACE2

Synonyms

Description

angiotensin I converting enzyme 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]

Chromosome

X (Chromosome progress)

Cytoband

p22.2

Chromosome location (bp)

15579156 - 15620271

Ensembl

ENSG00000130234 (version 73.37)

Entrez gene

59272

UniProt

Q9BYF1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BYF1

Antibodypedia

ACE2 antibodies
 

PROTEIN VIEW

? »
 
 
 
ACE2-001
 
ACE2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACE2-001 ENSP00000252519
ENST00000252519
Q9BYF1
Show all »
Show » Show » 805 92.5 Yes 1
ACE2-201 ENSP00000389326
ENST00000427411
Q9BYF1
Show all »
Show » Show » 805 92.5 Yes 1