MAP3K10

GENE INFORMATION

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Gene name

MAP3K10 (HGNC Symbol)

Synonyms

MEKK10, MLK2, MST

Description

mitogen-activated protein kinase kinase kinase 10 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.2

Chromosome location (bp)

40697651 - 40721482

Ensembl

ENSG00000130758 (version 73.37)

Entrez gene

4294

UniProt

Q02779 (UniProt - Evidence at protein level)

neXtProt

NX_Q02779

Antibodypedia

MAP3K10 antibodies
 

PROTEIN VIEW

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MAP3K10-001
 
MAP3K10-002
 
MAP3K10-003
 
MAP3K10-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAP3K10-001 ENSP00000253055
ENST00000253055
Q02779
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Show » Show » 954 103.7 No 0
MAP3K10-002 ENSP00000471916
ENST00000597986
M0R1J8
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Show » 180 20.3 No 0
MAP3K10-003 ENSP00000471116
ENST00000594951
Show » 67 7.6 No 0
MAP3K10-004 ENSP00000473021
ENST00000593502
M0R365
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Show » 122 13.8 No 0