PPAN

GENERAL INFORMATION

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Gene name

PPAN

Gene description

Peter pan homolog (Drosophila)

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Not detected

Protein evidence

Evidence at protein level

Protein localization

Nucleolar expression in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA043265
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Not detected

Organ

Expression



GENE INFORMATION

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Gene name

PPAN (HGNC Symbol)

Synonyms

BXDC3, SSF, SSF1, SSF2

Description

Peter pan homolog (Drosophila) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation. [provided by RefSeq, Nov 2010]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

10106289 - 10111634

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130810 (version 78.38)

Entrez gene

56342

UniProt

Q9NQ55 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQ55

Antibodypedia

PPAN antibodies


PROTEIN BROWSER

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ENST00000253107
 
ENST00000393793
 
ENST00000430370
 
ENST00000444703
 
ENST00000446223
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPAN-001 ENSP00000253107
ENST00000253107
Q9NQ55
Show all »
Show » Show » 473 53.2 No 0
PPAN-002 ENSP00000377382
ENST00000393793
A8MV53
Show all »
Show » 420 47.1 No 0
PPAN-003 ENSP00000410485
ENST00000446223
C9J3W3
Show all »
Show » 210 23.6 No 0
PPAN-004 ENSP00000415988
ENST00000430370
C9JHF7
Show all »
Show » 97 11 No 0
PPAN-009 ENSP00000415467
ENST00000444703
Show » 208 23.1 No 0