UBA1

GENE INFORMATION

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Gene name

UBA1 (HGNC Symbol)

Synonyms

A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X

Description

Ubiquitin-like modifier activating enzyme 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p11.3

Chromosome location (bp)

47190861 - 47215128

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130985 (version 78.38)

Entrez gene

7317

UniProt

P22314 (UniProt - Evidence at protein level)

neXtProt

NX_P22314

Antibodypedia

UBA1 antibodies
 

PROTEIN VIEW

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UBA1-001
 
UBA1-002
 
UBA1-003
 
UBA1-004
 
UBA1-005
 
UBA1-006
 
UBA1-007
 
UBA1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBA1-001 ENSP00000338413
ENST00000335972
P22314
Show all »
Show » Show » 1058 117.8 No 1
UBA1-002 ENSP00000366568
ENST00000377351
P22314
Show all »
Show » Show » 1058 117.8 No 1
UBA1-003 ENSP00000366481
ENST00000377269
Q5JRR6
Show all »
Show » Show » 506 56.9 No 1
UBA1-004 ENSP00000415033
ENST00000412206
Q5JRR9
Show all »
Show » Show » 271 29.2 No 0
UBA1-005 ENSP00000397816
ENST00000427561
Q5JRS1
Show all »
Show » Show » 173 18.6 No 0
UBA1-006 ENSP00000404796
ENST00000457753
Q5JRS3
Show all »
Show » Show » 195 20.7 No 0
UBA1-007 ENSP00000389583
ENST00000442035
Q5JRS0
Show all »
Show » Show » 284 30.8 No 0
UBA1-008 ENSP00000401101
ENST00000451702
Q5JRS2
Show all »
Show » Show » 234 25.1 No 0