HAUS8

GENERAL INFORMATION

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Gene name

HAUS8

Gene description

HAUS augmin-like complex, subunit 8

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Granular cytoplasmic expression in all tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA039406
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

HAUS8 (HGNC Symbol)

Synonyms

HICE1, MGC20533, NY-SAR-48

Description

HAUS augmin-like complex, subunit 8 (HGNC Symbol)

Entrez gene summary

HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]

Chromosome

19

Cytoband

p13.11

Chromosome location (bp)

17049729 - 17075625

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131351 (version 78.38)

Entrez gene

93323

UniProt

Q9BT25 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BT25

Antibodypedia

HAUS8 antibodies


PROTEIN BROWSER

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ENST00000253669
 
ENST00000448593
 
ENST00000593360
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HAUS8-001 ENSP00000253669
ENST00000253669
Q9BT25
Show all »
Show » Show » 410 44.9 No 0
HAUS8-002 ENSP00000470829
ENST00000593360
Q9BT25
Show all »
Show » Show » 349 38.5 No 0
HAUS8-004 ENSP00000395298
ENST00000448593
Q9BT25
Show all »
Show » Show » 409 44.8 No 0